Molecular and Cellular Therapies: New challenges and opportunities

Abstract

Gene therapy is suggested to be one of the most specific and efficient modulations for gene deficient diseases and
extended to other diseases like cancer and inflammation, even though there are still challenges to be faced, such
as specific and selective delivery, minimal to no toxicity, efficient metabolism, simplicity, and measurable efficiency.
It is important to identify and validate drug-able disease-specific targets for molecular and cellular therapies, while it
is equally important to have disease biomarkers to trace and define the biological effects of molecular and cellular
therapies. The importance and significance of allostery in molecular and cellular therapies and “allosteric disease”,
“allosteric effect”, and “allosteric drug” should be more carefully examined and validated. Cell therapy has been
attracting an increasing amount of consideration in the development of new treatments for diseases. Molecular and
Cellular Therapies (MCT) is a new, open-access journal, devoted to molecular mechanisms, preclinical and clinical
research and development of gene-, peptide-, protein-, and cell-based therapies