Integrating DNA with Functional Nanomaterials
DOI:
https://doi.org/10.13052/jsame2245-4551.122Abstract
DNA may be the most versatile molecule discovered to date. Beyond its well-
known central role in genetics, DNA has the potential to be a remarkably useful
technological material. It has been demonstrated as a scaffold for the assembly
of organic and inorganic nanomaterials [1]; a vehicle for drug delivery [2]; a
medium for computation [3]; and a possible wire for transporting electrical
signals [4]. A key factor in exploiting DNA in these ways is the ability to
integrate DNA with other materials. In this paper, we review two approaches
to forming DNA complexes with functional nanomaterials: (1) linking DNA
with single-wall carbon nanotubes (SWCNTs), which can then be used as
nanoscale electrical contacts for probing electron transport in DNA; and (2)
directed nanoassembly of Au nanoparticles using DNA/PNA (peptide nucleic
acid) hybrid scaffolds.
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